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Evodiamine Synergizes with Doxorubicin in the Treatment of Chemoresistant Human Breast Cancer without Inhibiting P-Glycoprotein

Drug resistance is one of the main hurdles for the successful treatment of breast cancer. The synchronous targeting of apoptosis resistance and survival signal transduction pathways may be a promising approach to overcome drug resistance. In this study, we determined that evodiamine (EVO), a major c...

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Main Authors: Wang, Shengpeng, Wang, Lu, Shi, Zhi, Zhong, Zhangfeng, Chen, Meiwan, Wang, Yitao
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4022620/
https://ncbi.nlm.nih.gov/pubmed/24830744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097512
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