Increased Expression of P-Glycoprotein and Doxorubicin Chemoresistance of Metastatic Breast Cancer Is Regulated by miR-298

MicroRNAs (miRNAs) are short, noncoding RNA molecules that regulate the expression of a number of genes involved in cancer; therefore, they offer great diagnostic and therapeutic targets. We have developed doxorubicin-resistant and -sensitive metastatic human breast cancer cell lines (MDA-MB-231) to...

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Detalhes bibliográficos
Main Authors: Bao, Lili, Hazari, Sidhartha, Mehra, Smriti, Kaushal, Deepak, Moroz, Krzysztof, Dash, Srikanta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378910/
https://ncbi.nlm.nih.gov/pubmed/22521303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.024
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