Increased Expression of P-Glycoprotein Is Associated with Doxorubicin Chemoresistance in the Metastatic 4T1 Breast Cancer Model

Development of drug resistance is one of the major causes of breast cancer treatment failure. The goal of this study was to understand the chemoresistance mechanism using the highly metastatic 4T1 breast cancer model, which emulates stage IV breast cancer in humans. The metastatic 4T1 breast cancer...

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Bibliografiske detaljer
Main Authors: Bao, Lili, Haque, Aliyya, Jackson, Kamilah, Hazari, Sidhartha, Moroz, Krzysztof, Jetly, Rachna, Dash, Srikanta
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2011
Fag:
Regular Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069823/
https://ncbi.nlm.nih.gov/pubmed/21281816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2010.10.029
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