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Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells

Fine tuning of the protein folding environment in subcellular organelles, such as mitochondria, is important for adaptive homeostasis and may participate in human diseases, but the regulators of this process are still largely elusive. Here, we have shown that selective targeting of heat shock protei...

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Detalhes bibliográficos
Main Authors: Siegelin, Markus D., Dohi, Takehiko, Raskett, Christopher M., Orlowski, Gregory M., Powers, Christine M., Gilbert, Candace A., Ross, Alonzo H., Plescia, Janet, Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069780/
https://ncbi.nlm.nih.gov/pubmed/21364280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44855
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