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Clinical Ramifications of the MHC Family Fc Receptor FcRn

INTRODUCTION: Knowledge that antibodies of the IgG isotype have remarkably extended persistence in circulation and are able to pass through cell barriers has substantial implications. While is well-established that so-called neonatal Fc receptor, FcRn, acts throughout life to confer these unusual pr...

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Detalhes bibliográficos
Main Authors: Roopenian, Derry C., Sun, Victor Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069705/
https://ncbi.nlm.nih.gov/pubmed/20848168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-010-9458-6
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