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ΔNp63, a Target of DEC1 and Histone Deacetylase 2, Modulates the Efficacy of Histone Deacetylase Inhibitors in Growth Suppression and Keratinocyte Differentiation

The p63 gene, a member of the p53 family, is expressed as TA and ΔN isoforms. ΔNp63 is the predominant isoform expressed in cells of epithelial origin and frequently overexpressed in cancers. However, what regulates p63 expression is uncertain. Here, we showed that ΔNp63 is regulated by the transcri...

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Bibliografske podrobnosti
Main Authors: Qian, Yingjuan, Jung, Yong-Sam, Chen, Xinbin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069406/
https://ncbi.nlm.nih.gov/pubmed/21317427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207241
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