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ΔNp63, a Target of DEC1 and Histone Deacetylase 2, Modulates the Efficacy of Histone Deacetylase Inhibitors in Growth Suppression and Keratinocyte Differentiation

The p63 gene, a member of the p53 family, is expressed as TA and ΔN isoforms. ΔNp63 is the predominant isoform expressed in cells of epithelial origin and frequently overexpressed in cancers. However, what regulates p63 expression is uncertain. Here, we showed that ΔNp63 is regulated by the transcri...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Qian, Yingjuan, Jung, Yong-Sam, Chen, Xinbin
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069406/
https://ncbi.nlm.nih.gov/pubmed/21317427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.207241
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