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Pirh2 E3 Ubiquitin Ligase Modulates Keratinocyte Differentiation Through p63

p63, a homologue of the tumor suppressor p53, is essential for the development of epidermis and limb. p63 is highly expressed in epithelial cell layer and acts as a molecular switch that initiates epithelial stratification. However, the mechanisms controlling p63 protein level is still far from full...

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Détails bibliographiques
Auteurs principaux: Jung, Yong-Sam, Qian, Yingjuan, Yan, Wensheng, Chen, Xinbin
Format: Artigo
Langue:Inglês
Publié: 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610774/
https://ncbi.nlm.nih.gov/pubmed/23235527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2012.466
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