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DEC1 Coordinates with HDAC8 to Differentially Regulate TAp73 and ΔNp73 Expression

P73, a member of the p53 family, plays a critical role in neural development and tumorigenesis. Due to the usage of two different promoters, p73 is expressed as two major isoforms, TAp73 and ΔNp73, often with opposing functions. Here, we reported that transcriptional factor DEC1, a target of the p53...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qian, Yingjuan, Zhang, Jin, Jung, Yong-Sam, Chen, Xinbin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3880278/
https://ncbi.nlm.nih.gov/pubmed/24404147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0084015
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