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ΔNp73 Modulates Nerve Growth Factor-Mediated Neuronal Differentiation through Repression of TrkA

p73, a member of the p53 family, expresses two classes of proteins: the full-length TAp73 and the N-terminally truncated ΔNp73. While TAp73 possesses many p53-like features, ΔNp73 is dominant negative towards TAp73 and p53 and appears to have distinct functions in tumorigenesis and neuronal developm...

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Autors principals: Zhang, Jin, Chen, Xinbin
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899982/
https://ncbi.nlm.nih.gov/pubmed/17353261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02112-06
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