The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor.

A downstream G-rich sequence (GRS), GGGGGAGGUGUGGG, has been previously shown to influence the efficiency of 3' end processing of the SV40 late polyadenylation signal. We have now defined several important parameters for GRS-mediated polyadenylation. The ability of the GRS to influence 3'...

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Bibliographische Detailangaben
Hauptverfasser: Bagga, P S, Ford, L P, Chen, F, Wilusz, J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1995
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC306907/
https://ncbi.nlm.nih.gov/pubmed/7784220
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