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The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor.

A downstream G-rich sequence (GRS), GGGGGAGGUGUGGG, has been previously shown to influence the efficiency of 3' end processing of the SV40 late polyadenylation signal. We have now defined several important parameters for GRS-mediated polyadenylation. The ability of the GRS to influence 3' end proces...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Bagga, P S, Ford, L P, Chen, F, Wilusz, J
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 1995
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306907/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7784220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.9.1625
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