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The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location.

The CstF polyadenylation factor is a multisubunit complex required for efficient cleavage and polyadenylation of pre-mRNAs. Using an RNase H-mediated mapping technique, we show that the 64-kDa subunit of CstF can be photo cross-linked to pre-mRNAs at U-rich regions located downstream of the cleavage...

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Detalles Bibliográficos
Publicado en:Mol Cell Biol
Autores principales: MacDonald, C C, Wilusz, J, Shenk, T
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 1994
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359194/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935383/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.10.6647
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