The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location.

The CstF polyadenylation factor is a multisubunit complex required for efficient cleavage and polyadenylation of pre-mRNAs. Using an RNase H-mediated mapping technique, we show that the 64-kDa subunit of CstF can be photo cross-linked to pre-mRNAs at U-rich regions located downstream of the cleavage...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	MacDonald, C C, Wilusz, J, Shenk, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC359194/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7935383/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.10.6647-6654.1994
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