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The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor.

A downstream G-rich sequence (GRS), GGGGGAGGUGUGGG, has been previously shown to influence the efficiency of 3' end processing of the SV40 late polyadenylation signal. We have now defined several important parameters for GRS-mediated polyadenylation. The ability of the GRS to influence 3' end proces...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Bagga, P S, Ford, L P, Chen, F, Wilusz, J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1995
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC306907/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7784220/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/23.9.1625
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