Complex Cell Cycle Abnormalities Caused by Human T-Lymphotropic Virus Type 1 Tax

Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell leukemia/lymphoma (ATL), a malignancy of CD4(+) T cells whose etiology is thought to be associated with the viral trans-activator Tax. We have shown recently that Tax can drastically upregulate the expression of p27(Ki...

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Main Authors: Yang, Liangpeng, Kotomura, Naoe, Ho, Yik-Khuan, Zhi, Huijun, Bixler, Sandra, Schell, Michael J., Giam, Chou-Zen
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2011
Assuntos:
Transformation and Oncogenesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067921/
https://ncbi.nlm.nih.gov/pubmed/21209109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00086-10
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