Mouse Cardiac Acyl Coenzyme A Synthetase 1 Deficiency Impairs Fatty Acid Oxidation and Induces Cardiac Hypertrophy

Long-chain acyl coenzyme A (acyl-CoA) synthetase isoform 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids and contributes the majority of cardiac long-chain acyl-CoA synthetase activity. To understand its functional role in the heart, we studied mice lacking ACSL1 globally (...

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Autori principali: Ellis, Jessica M., Mentock, Shannon M., DePetrillo, Michael A., Koves, Timothy R., Sen, Shiraj, Watkins, Steven M., Muoio, Deborah M., Cline, Gary W., Taegtmeyer, Heinrich, Shulman, Gerald I., Willis, Monte S., Coleman, Rosalind A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067914/
https://ncbi.nlm.nih.gov/pubmed/21245374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-10
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