Mouse Cardiac Acyl Coenzyme A Synthetase 1 Deficiency Impairs Fatty Acid Oxidation and Induces Cardiac Hypertrophy

Long-chain acyl coenzyme A (acyl-CoA) synthetase isoform 1 (ACSL1) catalyzes the synthesis of acyl-CoA from long-chain fatty acids and contributes the majority of cardiac long-chain acyl-CoA synthetase activity. To understand its functional role in the heart, we studied mice lacking ACSL1 globally (...

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Autors principals: Ellis, Jessica M., Mentock, Shannon M., DePetrillo, Michael A., Koves, Timothy R., Sen, Shiraj, Watkins, Steven M., Muoio, Deborah M., Cline, Gary W., Taegtmeyer, Heinrich, Shulman, Gerald I., Willis, Monte S., Coleman, Rosalind A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067914/
https://ncbi.nlm.nih.gov/pubmed/21245374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01085-10
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