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TIA1 Prevents Skipping of a Critical Exon Associated with Spinal Muscular Atrophy
Prevention of skipping of exon 7 during pre-mRNA splicing of Survival Motor Neuron 2 (SMN2) holds the promise for cure of spinal muscular atrophy (SMA), a leading genetic cause of infant mortality. Here, we report T-cell-restricted intracellular antigen 1 (TIA1) and TIA1-related (TIAR) proteins as i...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067828/ https://ncbi.nlm.nih.gov/pubmed/21189287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00945-10 |
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