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Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains

Studies involving limited numbers of rotavirus (RV) strains have shown that the viral gene 5 product, NSP1, can antagonize beta interferon (IFN-β) expression by inducing the degradation of IFN-regulatory factors (IRFs) (IRF3, IRF5, and IRF7) or a component of the E3 ubiquitin ligase complex responsi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Arnold, Michelle M., Patton, John T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067804/
https://ncbi.nlm.nih.gov/pubmed/21177809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01801-10
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