Rotavirus NSP1 Protein Inhibits Interferon-Mediated STAT1 Activation

Rotavirus (RV) replicates efficiently in intestinal epithelial cells (IECs) in vivo despite the activation of a local host interferon (IFN) response. Previously, we demonstrated that homologous RV efficiently inhibits IFN induction in single infected and bystander villous IECs in vivo. Paradoxically...

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Bibliographic Details
Main Authors: Sen, Adrish, Rott, Lusijah, Phan, Nguyen, Mukherjee, Gourab, Greenberg, Harry B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911692/
https://ncbi.nlm.nih.gov/pubmed/24131713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01501-13
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