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Rotavirus Degrades Multiple Interferon (IFN) Type Receptors To Inhibit IFN Signaling and Protects against Mortality from Endotoxin in Suckling Mice

STAT1 phosphorylation in response to exogenous interferon (IFN) administration can be inhibited by rotaviral replication both in vitro and in vivo. In addition many rotavirus strains are resistant to the actions of different IFN types. The regulation by rotaviruses (RVs) of antiviral pathways mediat...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sen, Adrish, Sharma, Ayushi, Greenberg, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730789/
https://ncbi.nlm.nih.gov/pubmed/29070687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01394-17
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