Rotavirus Degrades Multiple Interferon (IFN) Type Receptors To Inhibit IFN Signaling and Protects against Mortality from Endotoxin in Suckling Mice

STAT1 phosphorylation in response to exogenous interferon (IFN) administration can be inhibited by rotaviral replication both in vitro and in vivo. In addition many rotavirus strains are resistant to the actions of different IFN types. The regulation by rotaviruses (RVs) of antiviral pathways mediat...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Sen, Adrish, Sharma, Ayushi, Greenberg, Harry B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2017
Ämnen:
Pathogenesis and Immunity
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5730789/
https://ncbi.nlm.nih.gov/pubmed/29070687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01394-17
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