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Diversity of Interferon Antagonist Activities Mediated by NSP1 Proteins of Different Rotavirus Strains
Studies involving limited numbers of rotavirus (RV) strains have shown that the viral gene 5 product, NSP1, can antagonize beta interferon (IFN-β) expression by inducing the degradation of IFN-regulatory factors (IRFs) (IRF3, IRF5, and IRF7) or a component of the E3 ubiquitin ligase complex responsi...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3067804/ https://ncbi.nlm.nih.gov/pubmed/21177809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01801-10 |
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