Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

Virus-specific CD8 T cells are activated when their T-cell receptors (TCRs) recognize the specific viral peptide/major histocompatibility complex (MHC) class I (pMHC) complexes present on the surface of infected cells. Antibodies able to recognize the specific pMHC can mimic TCR specificity and both...

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Hlavní autoři: Sastry, Konduru S. R., Too, Chien Tei, Kaur, Kaval, Gehring, Adam J., Low, Lionel, Javiad, Alia, Pollicino, Teresa, Li, Li, Kennedy, Patrick T. F., Lopatin, Uri, Macary, Paul A., Bertoletti, Antonio
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067764/
https://ncbi.nlm.nih.gov/pubmed/21159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-10
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