Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

Virus-specific CD8 T cells are activated when their T-cell receptors (TCRs) recognize the specific viral peptide/major histocompatibility complex (MHC) class I (pMHC) complexes present on the surface of infected cells. Antibodies able to recognize the specific pMHC can mimic TCR specificity and both...

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Bibliografiset tiedot
Päätekijät: Sastry, Konduru S. R., Too, Chien Tei, Kaur, Kaval, Gehring, Adam J., Low, Lionel, Javiad, Alia, Pollicino, Teresa, Li, Li, Kennedy, Patrick T. F., Lopatin, Uri, Macary, Paul A., Bertoletti, Antonio
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2011
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067764/
https://ncbi.nlm.nih.gov/pubmed/21159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-10
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