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Complement-Dependent Lysis of Influenza A Virus-Infected Cells by Broadly Cross-Reactive Human Monoclonal Antibodies

We characterized human monoclonal antibodies (MAbs) cloned from influenza virus-infected patients and from influenza vaccine recipients by complement-dependent lysis (CDL) assay. Most MAbs active in CDL were neutralizing, but not all neutralizing MAbs can mediate CDL. Two of the three stalk-specific...

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Detalhes bibliográficos
Main Authors: Terajima, Masanori, Cruz, John, Co, Mary Dawn T., Lee, Jane-Hwei, Kaur, Kaval, Wilson, Patrick C., Ennis, Francis A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233150/
https://ncbi.nlm.nih.gov/pubmed/21994454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05193-11
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