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A Human CD4(+) T Cell Epitope in the Influenza Hemagglutinin Is Cross-Reactive to Influenza A Virus Subtypes and to Influenza B Virus

The hemagglutinin protein (HA) of the influenza virus family is a major antigen for protective immunity. Thus, it is a relevant target for developing vaccines. Here, we describe a human CD4(+) T cell epitope in the influenza virus HA that lies in the fusion peptide of the HA. This epitope is well co...

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Библиографические подробности
Главные авторы: Babon, Jenny Aurielle B., Cruz, John, Ennis, Francis A., Yin, Liusong, Terajima, Masanori
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416118/
https://ncbi.nlm.nih.gov/pubmed/22718815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.06325-11
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