The Level of Viral Antigen Presented by Hepatocytes Influences CD8 T-Cell Function

CD8 T cells exert their antiviral function through cytokines and lysis of infected cells. Because hepatocytes are susceptible to noncytolytic mechanisms of viral clearance, CD8 T-cell antiviral efficiency against hepatotropic viruses has been linked to their capacity to produce gamma interferon (IFN...

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Detalhes bibliográficos
Main Authors: Gehring, Adam J., Sun, Dianxing, Kennedy, Patrick T. F., Nolte-'t Hoen, Esther, Lim, Seng Gee, Wasser, Shanthi, Selden, Clare, Maini, Mala K., Davis, Dan M., Nassal, Michael, Bertoletti, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866017/
https://ncbi.nlm.nih.gov/pubmed/17202217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02415-06
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