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Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

Virus-specific CD8 T cells are activated when their T-cell receptors (TCRs) recognize the specific viral peptide/major histocompatibility complex (MHC) class I (pMHC) complexes present on the surface of infected cells. Antibodies able to recognize the specific pMHC can mimic TCR specificity and both...

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Autors principals: Sastry, Konduru S. R., Too, Chien Tei, Kaur, Kaval, Gehring, Adam J., Low, Lionel, Javiad, Alia, Pollicino, Teresa, Li, Li, Kennedy, Patrick T. F., Lopatin, Uri, Macary, Paul A., Bertoletti, Antonio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067764/
https://ncbi.nlm.nih.gov/pubmed/21159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-10
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