Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

Virus-specific CD8 T cells are activated when their T-cell receptors (TCRs) recognize the specific viral peptide/major histocompatibility complex (MHC) class I (pMHC) complexes present on the surface of infected cells. Antibodies able to recognize the specific pMHC can mimic TCR specificity and both...

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Detalhes bibliográficos
Main Authors: Sastry, Konduru S. R., Too, Chien Tei, Kaur, Kaval, Gehring, Adam J., Low, Lionel, Javiad, Alia, Pollicino, Teresa, Li, Li, Kennedy, Patrick T. F., Lopatin, Uri, Macary, Paul A., Bertoletti, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2011
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067764/
https://ncbi.nlm.nih.gov/pubmed/21159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-10
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