Targeting Hepatitis B Virus-Infected Cells with a T-Cell Receptor-Like Antibody

Virus-specific CD8 T cells are activated when their T-cell receptors (TCRs) recognize the specific viral peptide/major histocompatibility complex (MHC) class I (pMHC) complexes present on the surface of infected cells. Antibodies able to recognize the specific pMHC can mimic TCR specificity and both...

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Bibliographische Detailangaben
Hauptverfasser: Sastry, Konduru S. R., Too, Chien Tei, Kaur, Kaval, Gehring, Adam J., Low, Lionel, Javiad, Alia, Pollicino, Teresa, Li, Li, Kennedy, Patrick T. F., Lopatin, Uri, Macary, Paul A., Bertoletti, Antonio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067764/
https://ncbi.nlm.nih.gov/pubmed/21159876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01990-10
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