Three Residues in HIV-1 Matrix Contribute to Protease Inhibitor Susceptibility and Replication Capacity

Other than cleavage site mutations, there is little data on specific positions within Gag that impact on HIV protease inhibitor susceptibility. We have recently shown that non-cleavage site mutations in gag, particularly within matrix protein can restore replication capacity and further reduce prote...

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Bibliografiska uppgifter
Huvudupphovsmän: Parry, Chris M., Kolli, Madhavi, Myers, Richard E., Cane, Patricia A., Schiffer, Celia, Pillay, Deenan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2011
Ämnen:
Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067102/
https://ncbi.nlm.nih.gov/pubmed/21149628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01228-10
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