Importin α7 Is Essential for Zygotic Genome Activation and Early Mouse Development

Importin α is involved in the nuclear import of proteins. It also contributes to spindle assembly and nuclear membrane formation, however, the underlying mechanisms are poorly understood. Here, we studied the function of importin α7 by gene targeting in mice and show that it is essential for early e...

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Bibliografiske detaljer
Main Authors: Rother, Franziska, Shmidt, Tatiana, Popova, Elena, Krivokharchenko, Alexander, Hügel, Stefanie, Vilianovich, Larissa, Ridders, Michael, Tenner, Katja, Alenina, Natalia, Köhler, Matthias, Hartmann, Enno, Bader, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066239/
https://ncbi.nlm.nih.gov/pubmed/21479251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018310
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