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Nuclear Localization Signal and Protein Context both Mediate Importin α Specificity of Nuclear Import Substrates
The “classical” nuclear protein import pathway depends on importin α and importin β. Importin α binds nuclear localization signal (NLS)-bearing proteins and functions as an adapter to access the importin β-dependent import pathway. In humans, only one importin β is known to interact with importin α,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636818/ https://ncbi.nlm.nih.gov/pubmed/17000757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00708-06 |
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