In Vivo Analysis of Importin α Proteins Reveals Cellular Proliferation Inhibition and Substrate Specificity

The “classical” nuclear import pathway depends on importins α and β. Humans have only one importin β, while six α importins have been described. Whether or not distinct α importins are essential for specific import pathways in living human cells is unclear. We used RNA interference technology to spe...

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Hlavní autoři: Quensel, Christina, Friedrich, Beate, Sommer, Thomas, Hartmann, Enno, Kohler, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Cell Growth and Development
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC529023/
https://ncbi.nlm.nih.gov/pubmed/15542834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.23.10246-10255.2004
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