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Diversification of importin-α isoforms in cellular trafficking and disease states
The human genome encodes seven isoforms of importin α which are grouped into three subfamilies known as α1, α2 and α3. All isoforms share a fundamentally conserved architecture that consists of an N-terminal, autoinhibitory, importin-β-binding (IBB) domain and a C-terminal Arm (Armadillo)-core that...
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| Опубликовано в: : | Biochem J |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405237/ https://ncbi.nlm.nih.gov/pubmed/25656054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141186 |
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