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MOLECULAR BASIS FOR THE RECOGNITION OF PHOSPHORYLATED STAT1 BY IMPORTIN α5

Interferon-γ (IFN-γ) stimulation triggers tyrosine-phosphorylation of transcription factor STAT1 at position 701, which is associated with the switching from carrier-independent nucleocytoplasmic shuttling to carrier-mediated nuclear import. Unlike most substrates that carry a classical Nuclear Loca...

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Detalhes bibliográficos
Main Authors: Nardozzi, Jonathan, Wenta, Nikola, Yasuhara, Noriko, Vinkemeier, Uwe, Cingolani, Gino
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930068/
https://ncbi.nlm.nih.gov/pubmed/20643137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.013
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