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Nucleoporin Nup50 Stabilizes Closed Conformation of Armadillo repeat 10 in Importin α5
The human genome encodes six isoforms of importin α that show greater than 60% sequence similarity and remarkable substrate specificity. The isoform importin α5 can bind phosphorylated cargos such as STAT1 and Epstein-Barr Virus Nuclear Antigen 1, as well as the influenza virus polymerase subunit PB...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265882/ https://ncbi.nlm.nih.gov/pubmed/22130666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.315838 |
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