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Importin β contains a COOH-terminal nucleoporin binding region important for nuclear transport

Proteins containing a classical NLS are transported into the nucleus by the import receptor importin β, which binds to cargoes via the adaptor importin α. The import complex is translocated through the nuclear pore complex by interactions of importin β with a series of nucleoporins. Previous studies...

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Bibliographic Details
Main Authors: Bednenko, Janna, Cingolani, Gino, Gerace, Larry
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172684/
https://ncbi.nlm.nih.gov/pubmed/12885761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303085
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