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Importin β contains a COOH-terminal nucleoporin binding region important for nuclear transport

Proteins containing a classical NLS are transported into the nucleus by the import receptor importin β, which binds to cargoes via the adaptor importin α. The import complex is translocated through the nuclear pore complex by interactions of importin β with a series of nucleoporins. Previous studies...

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Autors principals: Bednenko, Janna, Cingolani, Gino, Gerace, Larry
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2172684/
https://ncbi.nlm.nih.gov/pubmed/12885761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200303085
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