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Differential use of importin-α isoforms governs cell tropism and host adaptation of influenza virus

Influenza A viruses are a threat to humans due to their ability to cross species barriers, as illustrated by the 2009 H1N1v pandemic and sporadic H5N1 transmissions. Interspecies transmission requires adaptation of the viral polymerase to importin-α, a cellular protein that mediates transport into t...

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Detalhes bibliográficos
Main Authors: Gabriel, Gülsah, Klingel, Karin, Otte, Anna, Thiele, Swantje, Hudjetz, Ben, Arman-Kalcek, Gökhan, Sauter, Martina, Shmidt, Tatiana, Rother, Franziska, Baumgarte, Sigrid, Keiner, Björn, Hartmann, Enno, Bader, Michael, Brownlee, George G., Fodor, Ervin, Klenk, Hans-Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105303/
https://ncbi.nlm.nih.gov/pubmed/21245837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1158
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