Importin α1 is required for nuclear import of herpes simplex virus proteins and capsid assembly in fibroblasts and neurons

Herpesviruses are large DNA viruses which depend on many nuclear functions, and therefore on host transport factors to ensure specific nuclear import of viral and host components. While some import cargoes bind directly to certain transport factors, most recruit importin β1 via importin α. We identi...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Döhner, Katinka, Ramos-Nascimento, Ana, Bialy, Dagmara, Anderson, Fenja, Hickford-Martinez, Ana, Rother, Franziska, Koithan, Thalea, Rudolph, Kathrin, Buch, Anna, Prank, Ute, Binz, Anne, Hügel, Stefanie, Lebbink, Robert Jan, Hoeben, Rob C., Hartmann, Enno, Bader, Michael, Bauerfeind, Rudolf, Sodeik, Beate
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773220/
https://ncbi.nlm.nih.gov/pubmed/29304174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006823
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