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Inner tegument proteins of Herpes Simplex Virus are sufficient for intracellular capsid motility in neurons but not for axonal targeting

Upon reactivation from latency and during lytic infections in neurons, alphaherpesviruses assemble cytosolic capsids, capsids associated with enveloping membranes, and transport vesicles harboring fully enveloped capsids. It is debated whether capsid envelopment of herpes simplex virus (HSV) is comp...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Buch, Anna, Müller, Oliver, Ivanova, Lyudmila, Döhner, Katinka, Bialy, Dagmara, Bosse, Jens B., Pohlmann, Anja, Binz, Anne, Hegemann, Maike, Nagel, Claus-Henning, Koltzenburg, Martin, Viejo-Borbolla, Abel, Rosenhahn, Bodo, Bauerfeind, Rudolf, Sodeik, Beate
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761964/
https://ncbi.nlm.nih.gov/pubmed/29284065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006813
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