Enzymatic Blockade of the Ubiquitin-Proteasome Pathway

Ubiquitin-dependent processes control much of cellular physiology. We show that expression of a highly active, Epstein-Barr virus-derived deubiquitylating enzyme (EBV-DUB) blocks proteasomal degradation of cytosolic and ER-derived proteins by preemptive removal of ubiquitin from proteasome substrate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ernst, Robert, Claessen, Jasper H. L., Mueller, Britta, Sanyal, Sumana, Spooner, Eric, van der Veen, Annemarthe G., Kirak, Oktay, Schlieker, Christian D., Weihofen, Wilhelm A., Ploegh, Hidde L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2011
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3066133/
https://ncbi.nlm.nih.gov/pubmed/21468303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000605
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