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A functional proteomics approach links the ubiquitin-related modifier Urm1 to a tRNA modification pathway
Urm1 is a highly conserved ubiquitin-related modifier of unknown function. A reduction of cellular Urm1 levels causes severe cytokinesis defects in HeLa cells, resulting in the accumulation of enlarged multinucleated cells. To understand the underlying mechanism, we applied a functional proteomics a...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584574/ https://ncbi.nlm.nih.gov/pubmed/19017811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808756105 |
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