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A Functional Ubiquitin-Specific Protease Embedded in the Large Tegument Protein (ORF64) of Murine Gammaherpesvirus 68 Is Active during the Course of Infection

All herpesviruses contain a ubiquitin (Ub)-specific cysteine protease domain embedded within their large tegument protein, based on homology with the corresponding sequences of UL36 from herpes simplex virus type 1 and M48 from murine cytomegalovirus. This type of activity has yet to be demonstrated...

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Detalhes bibliográficos
Main Authors: Gredmark, Sara, Schlieker, Christian, Quesada, Victor, Spooner, Eric, Ploegh, Hidde L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045495/
https://ncbi.nlm.nih.gov/pubmed/17634221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01149-07
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