Φορτώνει......
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity
The pregnane X receptor (PXR) is the molecular target for catatoxic steroids such as pregnenolone 16α-carbonitrile (PCN), which induce cytochrome P450 3A (CYP3A) expression and protect the body from harmful chemicals. In this study, we demonstrate that PXR is activated by the toxic bile acid lithoch...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , , , , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The National Academy of Sciences
2001
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC30660/ https://ncbi.nlm.nih.gov/pubmed/11248085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051551698 |
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