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Lithocholic acid induction of the FGF19 promoter in intestinal cells is mediated by PXR

AIM: To study the effect of the toxic secondary bile acid lithocholic acid (LCA) on the expression of fibroblast growth factor 19 (FGF19) in intestinal cells and to characterize the pregnane-X-receptor (PXR) response of the FGF19 promoter region. METHODS: The intestinal cell line LS174T was stimulat...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Wistuba, Wolfgang, Gnewuch, Carsten, Liebisch, Gerhard, Schmitz, Gerd, Langmann, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250623/
https://ncbi.nlm.nih.gov/pubmed/17696253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i31.4230
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