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Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes
Monocytes are precursors of macrophages. Here we demonstrate that macrophage colony-stimulating factor (M-CSF)-dependent differentiation of primary human monocytes from healthy volunteers induces transcription of SREBP-1c target genes required for fatty acid (FA) biosynthesis and impairs transcripti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2867858/ https://ncbi.nlm.nih.gov/pubmed/20385828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912059107 |
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