Role of Extracellular Hemoglobin in Thrombosis and Vascular Occlusion in Patients with Sickle Cell Anemia

Sickle cell anemia (SCA) is a common hemolytic disorder caused by a gene mutation in the β-globin subunit of hemoglobin (Hb) and affects millions of people. The intravascular hemolysis releases excessive amount of extracellular hemoglobin (ECHb) into plasma that causes many cellular dysfunctions in...

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Bibliographic Details
Main Authors: Zhou, Zhou, Behymer, Molly, Guchhait, Prasenjit
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2011
Subjects:
Review Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065893/
https://ncbi.nlm.nih.gov/pubmed/21490767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/918916
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