Φορτώνει......
Design of a novel nucleoside analog as potent inhibitor of the NAD(+) dependent deacetylase, SIRT2
Sirtuins (class III histone deacetylase) are evolutionarily conserved NAD(+)-dependent enzymes that catalyze the deacetylation of acetyl-lysine residues of histones and other target proteins. Because of their associations in various pathophysiological conditions, the identification of small molecule...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer Netherlands
2011
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3065595/ https://ncbi.nlm.nih.gov/pubmed/22132052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-011-9069-4 |
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