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The nucleoside analog clitocine is a potent and efficacious readthrough agent
Nonsense mutations resulting in a premature stop codon in an open reading frame occur in critical tumor suppressor genes in a large number of the most common forms of cancers and are known to cause or contribute to the progression of disease. Low molecular weight compounds that induce readthrough of...
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Publicado no: | RNA |
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Main Authors: | , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5340919/ https://ncbi.nlm.nih.gov/pubmed/28096517 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.060236.116 |
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