Preclinical Properties of (18)F-AV-45: A PET Agent for Aβ Plaques in the Brain

β-amyloid plaques (Aβ plaques) in the brain, containing predominantly fibrillary Aβ peptide aggregates, represent a defining pathologic feature of Alzheimer disease (AD). Imaging agents targeting the Aβ plaques in the living human brain are potentially valuable as biomarkers of pathogenesis processe...

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Detalhes bibliográficos
Main Authors: Choi, Seok Rye, Golding, Geoff, Zhuang, Zhiping, Zhang, Wei, Lim, Nathaniel, Hefti, Franz, Benedum, Tyler E., Kilbourn, Michael R., Skovronsky, Daniel, Kung, Hank F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065020/
https://ncbi.nlm.nih.gov/pubmed/19837759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.109.065284
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